Short synthesis and anti-rhinoviral activity of imidazo[1,2-a]pyridines: The effect of acyl groups at 3-position

Authors
Hamdouchi, C Ezquerra, J Vega, JA Vaquero, JJ Alvarez-Builla, J Heinz, BA
Citation
C. Hamdouchi et al., Short synthesis and anti-rhinoviral activity of imidazo[1,2-a]pyridines: The effect of acyl groups at 3-position, BIOORG MED, 9(10), 1999, pp. 1391-1394
Citations number
10
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
10
Year of publication
1999
Pages
1391 - 1394
Database
ISI
SICI code
0960-894X(19990517)9:10<1391:SSAAAO>2.0.ZU;2-3
Abstract
Various 2-amino-3-acyl-6-[(E)-1-phenyl-2-N-methylcarbamoylvinyl]-imidazo[1, 2-a]pyridines, structurally related to Enviroxime were prepared to determin e the effect of acyl groups on the anti-rhinoviral activity. A short and ef ficient means for the construction of the imidazo nucleus as well as biolog ical evaluation of the final compounds are disclosed. (C) 1999 Elsevier Sci ence Ltd. All rights reserved.