AML-M0: A review of laboratory features and proposal of new diagnostic criteria

In 1991, the FAB group published a proposal to designate acute leukemias wi th minimal signs of myeloid differentiation as AML-M0. This proposal was me ant to offer a provisional basis for the study of immature myeloid forms, w ith the understanding that it was susceptible to changes and improvements w ith new information derived from the laboratory. Since then there have been a number of reports detailing the biological and clinical features of pati ents with AML-M0. In this article we review the laboratory data acquired fr om various sources and suggest a partial modification of diagnostic criteri a. (C) 1999 by Academic Press.