Human herpes virus-6 seroprevalence and leukaemias: a case-control study

Authors
Gentile, G Mele, A Ragona, G Faggioni, A Zompetta, C Tosti, ME Visani, G Castelli, G Pulsoni, A Monarca, B Martino, P Mandelli, F
Citation
G. Gentile et al., Human herpes virus-6 seroprevalence and leukaemias: a case-control study, BR J CANC, 80(7), 1999, pp. 1103-1106
Citations number
25
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
80
Issue
7
Year of publication
1999
Pages
1103 - 1106
Database
ISI
SICI code
0007-0920(199906)80:7<1103:HHVSAL>2.0.ZU;2-E
Abstract
The relationships between acute myeloid leukaemia (AML), acute lymphocytic leukaemia (ALL), chronic myeloid leukaemia (CML) and refractory anaemia wit h excess of blasts (RAEB) and human herpes virus (HHV)-6 antibody level wer e investigated in a multicentre case-control study. An association between increased HHV-6 seropositivity and geometric mean titre ratio with AML was shown: P for trend = 0.022, adjusted odds ratio 1.20, 95% confidence interv al 1.07-1.33 respectively. No association was found between HHV-6 and ALL, CML or RAEB.