Serological testing in screening for adult celiac disease

Citation
Hr. Gillett et Hj. Freeman, Serological testing in screening for adult celiac disease, CAN J GASTR, 13(3), 1999, pp. 265-269
Citations number
55
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
CANADIAN JOURNAL OF GASTROENTEROLOGY
ISSN journal
08357900 → ACNP
Volume
13
Issue
3
Year of publication
1999
Pages
265 - 269
Database
ISI
SICI code
0835-7900(199904)13:3<265:STISFA>2.0.ZU;2-S
Abstract
Assays for celiac related antibodies an becoming widely available, and the present review aims to clarify the use of these investigations in the diagn osis of management of and screening for adult celiac disease. The sensitivi ties and specificities of various antibody tests are discussed, along with their clinical use as an adjunct to small bowel biopsy, and as a first-line investigation for patients with atypical symptoms of celiac disease or pat ients at high risk of developing sprue.