Study objectice: Bronchoscopic technique is not standardized. Controversies
exist with regard to premedication with sedatives before the test. To eval
uate safety and efficacy of conscious sedation, we studied 100 randomized p
atients undergoing diagnostic bronchoscopy; patients received premedication
with lidocaine spray and atropine sulfate IM (nonsedation group; 50 patien
ts) or lidocaine spray, atropine IM and diazepam IV (sedation group; 50 pat
ients).
Methods and results: Monitoring during flexible fiberoptic bronchoscopy inc
luded continuous ECG and pulse oximetry. The procedure could not be complet
ed in sir; patients. None received premedication with diazepam; among the p
atients who ended the examination, tolerance to the examination (visual ana
logue scale, 0 to 100; 0 = excellent; 100 = unbearable) was better in the s
edation group. Low anxiety, male sex, but not age were also associated with
improved patient tolerance to the test. Oxygen desaturation occurred in 17
% of patients, and it was not more frequent after diazepam treatment.
Conclusion: In our study, sedation had a beneficial effect on patient toler
ance and rarely induced significant alterations in cardiorespiratory monito
ring parameters.