Positive antineutrophil cytoplasmic antibodies-associated vasculitis presenting with hemoptysis and a mediastinal mass

A patient with end-stage renal failure, due to IgA nephropathy, was found t o have a mediastinal mass. Biopsy specimen of the mass showed a necrotizing vasculitis. Antineutrophil antibodies to myeloperoxidase were strongly pos itive. To our knowledge, no case of a mediastinal mass due vasculitis has b een reported in the literature, and our observation should lead to broadeni ng of the spectrum of clinical manifestations of vasculitis.