The diagnosis of feline idiopathic lower urinary tract disease (iLUTD) depe
nds on excluding other causes of hematuria, dysuria, and pollakiuria. Becau
se no single test or procedure is pathognomonic for iLUTD, a combination of
tests is recommended to establish diagnosis. Comprehensive diagnostic eval
uation of the lower urinary tract may encompass a complete history and phys
ical examination, hemogram and serum chemistry profile, complete urinalysis
, quantitative urine culture for aerobic bacteria, survey abdominal radiogr
aphy, contrast urethrocystography, ultrasonography, urethrocystoscopy, and
surgical biopsy.