BACKGROUND. The advantages of using tumescent anesthesia for ambulatory phl
ebectomy have recently been described. Previously, tumescent solutions have
avoided epinephrine for concerns of toxicity given the large volume of ane
sthetic sometimes used.
OBJECTIVE. TO evaluate the efficacy and safety of using epinephrine in the
tumescent anesthesia solution during ambulatory phlebectomy.
METHODS. Over the course of 1 year, epinephrine in the concentration of 1:1
00,000 was added to the tumescent solution of patients undergoing ambulator
y phlebectomy. A retrospective review of 94 sequential patients was perform
ed to determine the rate of complications associated with the procedure.
RESULTS. The complication rate was considerably improved using tumescent li
docaine with epinephrine compared to a previously performed study of tumesc
ent lidocaine without epinephrine. The rate of hematoma was decreased to ni
l while the rate of hyperpigmentation decreased from 3.6% to 0%. Overall, t
he rate of complications was improved when epinephrine was added to the tum
escent lidocaine solution. Blood pressure measured every 5 minutes and hear
t rate measured continuously did not significantly change before, during or
after infiltration of the anesthetic solution.
CONCLUSIONS. Epinephrine in appropriate concentrations is clearly safe when
used in the tumescent anesthetic solution during ambulatory phlebectomy an
d should be used to reduce the incidence of hematoma and hyperpigmentation.