Pregnancy with primary tubal placental site trophoblastic tumor - A case report and literature review

Placental site trophoblastic tumor (PSTT) is a rare trophoblastic neoplasm with malignant potential. The diagnosis and prognosis of this rare disease remain difficult. A case of tubal PSTT with the primary manifestation of in ternal bleeding at 30 weeks' gestation is presented. Emergency exploratory laparotomy and right partial salpingectomy were performed initially. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy we re done immediately after cesarean section at 34 weeks' gestation. No furth er adjuvant therapy was given after surgery. No evidence of tumor recurrenc e or signs of metastasis were noted during 12 months of follow-up. Heteroto pic pregnancy, one with intrauterine normal pregnancy and the other with im planting in the right fallopian tube and placental site trophoblastic tumor transformation, was proposed. To our knowledge, this is the first such cas e in the English literature. (C) 1999 Academic Press.