Depression and suicidal intentions as a side effect of high dosage interferon or therapy - two cases

Authors
Windemuth, D Bacharach-Buhles, M Hoffmann, K Altmeyer, P
Citation
D. Windemuth et al., Depression and suicidal intentions as a side effect of high dosage interferon or therapy - two cases, HAUTARZT, 50(4), 1999, pp. 266-269
Citations number
4
Categorie Soggetti
Dermatology
Journal title
HAUTARZT
ISSN journal
00178470 → ACNP
Volume
50
Issue
4
Year of publication
1999
Pages
266 - 269
Database
ISI
SICI code
0017-8470(199904)50:4<266:DASIAA>2.0.ZU;2-4
Abstract
Adjuvant therapy with interferon for malignant melanoma causes neurotoxic s ide effects such as depression. The biochemical mechanisms are unknown. We report two cases with both depression and amnesia. In one case, attempted s uicide was a companied by 7 h of amnesia. The diagnostic classification and possible explanations for the amnesia secondary to interferon thera py are reviewed.