Three-dimensional endometrial volume calculation and pregnancy rate in an in-vitro fertilization programme

This study was designed to investigate the role of three-dimensional (3D) e ndometrial ultrasound in predicting the outcome of an in-vitro fertilizatio n (IVF) programme, In 47 IVF cycles measurements of endometrial thickness a nd volume, as assessed by 3D transvaginal ultrasound on the day of oocyte. retrieval, and concentrations of oestradiol and progesterone in the same pa tient sampled on the day of sonography, were related to the occurrence of a successful implantation. The overall pregnancy rate was 31.9% (15/47), Fif teen pregnant patients had a mean endometrial thickness and volume of 10.8 +/- 2.3 mm (mean +/- SD) and 4.9 +/- 2.2 ml, respectively. Thirty-two non-p regnant patients had corresponding measurements of 11.8 +/- 3.4 mm and 5.8 +/- 3.4 ml respectively. Endometrial thickness varied widely in both groups , in pregnant patients from 6.9 to 16.0 mm, in non-pregnant patients from 6 .5 to 21.1 mm, Oestradiol concentrations were not significantly correlated with either endometrial thickness or volume. The conclusion from the presen t data is that 3D volume estimation of the endometrium as well as analysis of endometrial thickness on the day of oocyte retrieval had no predictive v alue for conception in IVF cycles.