Low-noise amperometric detector for use in capillary electrophoresis

A low noise amperometric detector suitable for capillary electrophoresis ha s been constructed from integrated operational amplifiers with low noise an d low input bias current. It includes a potentiostat and a vertical wall-je t detection cell. The circuit design of the potentiostat, the construction of the detection cells, and methods for minimizing the noise are described. Performance tests of the detector were performed for the determination of catecholmines.