Intrabronchial Aspergillus nidulans infection in an immunocompetent man

We describe the first report of intrabronchial Aspergillus nidulans infecti on in an immunocompetent patient, which fit the description of bronchocentr ic granulomatosis. The patient had a history of accidental aspiration of li ght grade oil. Fiberoptic bronchoscopy revealed that the right B(4)aii alph a was obstructed. Endobronchial biopsy specimens contained fungal hyphae, T he fungus was confirmed to be Aspergillus nidulans by culture. We suspected that aspiration of light grade oil had injured the bronchial mucosa, after which airborne Aspergillus nidulans had entered the lesion and multiplied. Intrabronchial fungal infection can occur in a healthy person without immu nologic abnormalities, if a bronchial lesion provides an entry portal.