Results of special studies with alendronate

Major Phase III studies were planned to address basic issues regarding the effectiveness and safety of alendronate. However, 3 special studies were de signed to provide information regarding the effectiveness and safety of ale ndronate therapy for postmenopausal osteoporosis that complement the result of the large Phase III osteoporosis trials, addressing the duration of the drug's antiresorptive effect after withdrawal of therapy the effects of al endronate therapy in more elderly subjects and a comparison of alendronate with another treatment for osteoporosis.