Objective: The purpose of this study was to examine the timing and conseque
nces of suicide attempts by self-poisoning during pregnancy. Methods: A pop
ulation-based prospective study was organised in the toxicological in-patie
nt hospital in Budapest which is responsible for health services for adult
inhabitants poisoned by ingesting chemicals in Budapest and the surrounding
area involving 3 million people between 1985 and 1993. All women aged betw
een 16 and 50 years (22 969) who were admitted to the study hospital due to
suicide attempts by drug ingestion were examined by a sensitive serum preg
nancy test. Results: Of 559 self-poisoned pregnant women, two died. The pea
k period of suicide attempts was found to be in the first postconceptual mo
nth and its majority resulted in a very early fetal loss. The second highes
t figure was recorded in the second postconceptual month. Thus, 61% of suic
ide attempts occurred before the third postconceptual month. Later pregnanc
ies had a significantly lower proportion of attempting suicide parallel wit
h advanced fetal development. Conclusions: Most suicide attempts by self-po
isoning occurred after the early recognition of unwanted pregnancies and mo
st resulted in a very early fetal loss. Pregnancies with advanced gestation
months had a significantly lower proportion of attempting suicide, (C) 199
9 International Federation of Gynecology and Obstetrics.