BIOSYNTHETIC SHORT ACTIVATION OF THE 2,3,6-TRIDEOXGSUGAR L-RHODINOSE

The successful incorporation of non-activated [2,3-H-2(2)]-L-rhodinose 4b into landomycin A 7 proves the existence of a short activation pat hway for L-rhodinose 4; this result provides evidence of a general sav ing pathway for deoxy-sugar building blocks and their biosynthetic int ermediates, respectively, which become accidentally deactivated during the biosynthetic deoxygenation cascades.