A tetraploid fetus with an unusual facial appearance and multiple cong
enital anomalies (large cerebral lateral ventricles: lung, cardiac, an
d genital abnormalities) is reported. Chromosome analysis was performe
d on amniocytes and fetal blood lymphocytes. A comparison is made with
other reported cases (nine liveborn infants and one 17.2-week-old fet
us). (C) 1997 by John Wiley & Sons, Ltd.