Coexisting preexcitation syndrome and intermittent heart block presenting as neonatal seizures

Preexcitation Plus Intermittent Heart Block. An infant presented with neona tal syncope and seizures. An ECG showed preexcitation pattern, most compati ble with Wolff-Parkinson-White (WPW) syndrome. Rhythm monitoring during an event demonstrated prolonged periods of complete AV block with no ventricul ar escape mechanism. We postulated that ventricular asystole was initiated by mechanical or autonomic influences on the accessory pathway and sustaine d by electrophysiologic interactions between the accessory pathway and the junctional escape focus. This is the first case report of a newborn having coexisting congenital AV block and WPW syndrome. (J Cardiovasc Electrophysi ol, Vol. 10, pp. 736-740, May 1999).