Clay-catalyzed conversion of 2,2-disubstituted malononitriles to 2-oxazolines: Towards unnatural amino acids

Authors
Jnaneshwara, GK Deshpande, VH Bedekar, AV
Citation
Gk. Jnaneshwara et al., Clay-catalyzed conversion of 2,2-disubstituted malononitriles to 2-oxazolines: Towards unnatural amino acids, J CHEM R-S, (4), 1999, pp. 252-253
Citations number
23
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
4
Year of publication
1999
Pages
252 - 253
Database
ISI
SICI code
0308-2342(199904):4<252:CCO2MT>2.0.ZU;2-J
Abstract
Acidic clay catalyzed reaction of malononitrile derivatives with an excess of 1,2-aminoalcohol furnishes mono-oxazolines selectively; a simple strateg y to prepare 2,2-dialkyl-3-aminopropionic acid derivatives is presented.