Preparation of tert-butyl 6-aminopenicillanate and its 6-oxo and 6-diazo derivatives

Authors
Veinberg, G Vorona, M Musel, D Grigan, N Lukevics, E
Citation
G. Veinberg et al., Preparation of tert-butyl 6-aminopenicillanate and its 6-oxo and 6-diazo derivatives, J CHEM R-S, (4), 1999, pp. 270-271
Citations number
9
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
4
Year of publication
1999
Pages
270 - 271
Database
ISI
SICI code
0308-2342(199904):4<270:POT6AI>2.0.ZU;2-V
Abstract
A 1:1 1,4-dioxane-tert-butyl acetate mixture and BF3 etherate were used for an effective 6-aminopenicillanic acid conversion into the tert-butyl ester (64 +/- 3% yield) which could be easily transformed into tert-butyl 6-oxo- and 6-diazo-penicillanates.