Due to the low prevalence of hemangiopericytomas (HPCs), data on the biophy
siological characteristics of this tumor are rare. Positron emission tomogr
aphy (PET) demonstrated a sixfold increased uptake of [C-11]methionine and
hyperperfusion in the HPC, whereas glucose utilization was decreased in thi
s area. This low glucose utilization is in contrast to the high [C-11]methi
onine uptake and the malignancy of these tumors. The characteristics of HPC
s in PET described herein for the first time offer additional diagnostic cr
iteria and may help especially to differentiate these tumors from meningiom
as.