We developed an in vitro human kidney model to study the intrarenal pelvic
pressures generated during percutaneous nephroscopy. Higher intrapelvic pre
ssures were associated with nephroscopy sheaths of smaller caliber and grea
ter length. In addition, the position of the sheath within the kidney marke
dly influenced intrapelvic pressure. The results of this study have influen
ced our practice and are especially important during eases involving percut
aneous removal of infected urinary calculi and transitional-cell carcinoma.