Determination of the distance dependence and experimental effects for modified SERS substrates based on self-assembled monolayers formed using alkanethiols
Bj. Kennedy et al., Determination of the distance dependence and experimental effects for modified SERS substrates based on self-assembled monolayers formed using alkanethiols, J PHYS CH B, 103(18), 1999, pp. 3640-3646
Modified SERS (surface-enhanced Raman scattering) substrates are based on s
elf-assembled monolayers (SAMs) formed from compounds such as alkanethiols.
Chain lengths ranging from ethanethiol to octadecanethiol were used to inv
estigate properties of modified SERS substrates. These properties include d
etermining the magnitude of the SERS electromagnetic enhancement, developin
g a sensitivity factor for detecting aromatic compounds, and evaluating SER
S substrates for performance characteristics such as stability and solvent
effects. A SERS electromagnetic enhancement was determined to be 2.1 x 10(3
) for detecting aromatic compounds. The effects of experimental conditions
on the SERS detection process were addressed. SERS sensitivity was shown to
be highly dependent upon a correlation between the SERS interfacial distan
ce dependence and a hydrophobic effect exhibited by the alkyl chain of the
thiol. The distance dependence was more significant than the hydrophobic ef
fect for detecting aromatic compounds. For comparison to the electromagneti
c enhancement, a SERS sensitivity factor was determined for detecting benze
ne in wafer and in organic solvents. Experimental stability issues, such as
solvent and laser exposure, were shown to affect the sensitivity of modifi
ed SERS substrates. 1-Propanethiol exhibited the strongest sensitivity and
stability; under all solvent and experimental conditions.