On the effect of gadolinium in neutron capture therapy

Citation
Zb. Alfassi et al., On the effect of gadolinium in neutron capture therapy, J RAD NUCL, 240(2), 1999, pp. 687-687
Citations number
5
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
ISSN journal
02365731 → ACNP
Volume
240
Issue
2
Year of publication
1999
Pages
687 - 687
Database
ISI
SICI code
0236-5731(199905)240:2<687:OTEOGI>2.0.ZU;2-F
Abstract
The possibility of (n,gamma) reaction for cancer therapy is discussed in co nnection with gadolinium due to its exceptionally high cross section. It is argued that the therapeutic effect is not only due to Auger electrons but also to the recoil of the Gd atom. If the Gd atom is bound to the DNA it wi ll cause several raptures in the same DNA molecule leading to death of the cancerous cells.