The alpha-ketoamide group: a new motif for the elicitation of catalytic antibodies for acyl-transfer reactions

Authors
Taylor, MJ Yli-Kauhaluoma, JT Ashley, JA Wirsching, P Lerner, RA Janda, KD
Citation
Mj. Taylor et al., The alpha-ketoamide group: a new motif for the elicitation of catalytic antibodies for acyl-transfer reactions, J CHEM S P1, (9), 1999, pp. 1133-1134
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
9
Year of publication
1999
Pages
1133 - 1134
Database
ISI
SICI code
0300-922X(19990507):9<1133:TAGANM>2.0.ZU;2-H
Abstract
An alpha-ketoamide hapten elicited a monoclonal antibody that catalyzed the hydrolyses of esters and carbamates via either a covalent intermediate or direct addition of water.