Ga. Poland et al., DETERMINATION OF DELTOID FAT PAD THICKNESS - IMPLICATIONS FOR NEEDLE LENGTH IN ADULT IMMUNIZATION, JAMA, the journal of the American Medical Association, 277(21), 1997, pp. 1709-1711
Objective.-To measure deltoid fat pad thickness and determine the opti
mal needle length for deltoid intramuscular immunization in healthy ad
ults. Design, Setting, and Participants.-Prospective study of 220 heal
thy health care workers (126 women, 94 men) at the Mayo Medical Center
, Rochester, Minn. Main Outcome Measures.-Deltoid fat pad thickness de
termined by high-resolution ultrasound scanning, weight, height, and m
id-deltoid arm circumference. Results.-We found a highly significant d
ifference between women and men in deltoid fat pad thickness, with wom
en having a thicker deltoid fat pad (11.7 vs 8.3 mm; P<.001), Women ha
d a greater deltoid skin-fold thickness than men (34.7 vs 17.2 mm, P<.
001) and an equal body mass index, According to the ultrasound finding
s, a standard 16-mm (5/8-in) needle would not have reached 5 mm into m
uscle in 17% (16/94) of men and 48.4% (61/126) of women in this study.
Conclusions.-Among healthy adults of the age range we studied, the fo
llowing needle lengths appear to be appropriate for true deltoid intra
muscular immunization: For men across the weight ranges we studied (59
-118 kg), use of a 25-mm (1-in) needle would result in at least 5 mm o
f muscle penetration in all subjects. For women who weighed less than
60 kg, a 16-mm (5/8-in) needle would be sufficient to achieve muscle p
enetration of 5 mm. For women between 60 and 90 kg, a 25-mm (1-in) nee
dle would be sufficient, and women greater than 90 kg would require a
38-mm (1.5-in) needle to ensure intramuscular administration.