Prenatal detection of extra structurally abnormal chromosomes (ESACs): Newcases and a review of the literature

Authors
Hastings, RJ Nisbet, DL Waters, K Spencer, T Chitty, LS
Citation
Rj. Hastings et al., Prenatal detection of extra structurally abnormal chromosomes (ESACs): Newcases and a review of the literature, PRENAT DIAG, 19(5), 1999, pp. 436-445
Citations number
45
Categorie Soggetti
Reproductive Medicine","Medical Research Diagnosis & Treatment
Journal title
PRENATAL DIAGNOSIS
ISSN journal
01973851 → ACNP
Volume
19
Issue
5
Year of publication
1999
Pages
436 - 445
Database
ISI
SICI code
0197-3851(199905)19:5<436:PDOESA>2.0.ZU;2-T
Abstract
We present 16 cases, 10 de novo and 6 familial, in which extra structurally abnormal chromosomes (ESACs) were diagnosed prenatally and identified by f luorescence in situ hybridization (FISH) studies with follow up from birth. We review the literature on prenatally diagnosed ESACs arising de novo and suggest a management protocol for these cases. Copyright (C) 1999 John Wil ey & Sons, Ltd.