Communication distance in the intercellular signaling by cyto chemokine orautacoid

Characteristic properties of signaling processes are studied by a single ce ll model in the intercellular transport. The diffusion equation is solved f or molecules secreted from a spherical cell under the boundary conditions o f prescribed fluxes at the cell surface, The solution is physicochemically compared with another one corresponding to constant source at the cell surf ace by Francis and Palsson.(1)) Discussion is given on communication distan ces (similar to 50 mu m) estimated for human cytokines.