Thymoma and hypogammaglobulinemia, Good's syndrome: a case report and literature review.

Introduction. - Good's syndrome is defined as the association of thymoma, h ypogammaglobulinemia, and repetitive bronchopulmonary infections. We report one case and review the clinical and immunogical features of this syndrome . Exegesis. - We describe the case of a 67-year-old man who presented with bo th severe bronchopulmonary infection resistant to antibiotherapy and thymom a. Definite diagnosis was based on the existence of hypogammaglobulinemia. Treatment with intravenous immunoglobulins led to positive outcome. Conclusion. - Good's syndrome occurs in only 5% of parathymic diseases. To prevent futher bronchial tube destruction and pulmonary surgery, it must be diagnosed and treated early. (C) 1999 Elsevier, Paris.