Tablets in stool? An everyday problem!

Citation
Lv. Schuerch et al., Tablets in stool? An everyday problem!, SCHW MED WO, 129(17), 1999, pp. 670-673
Citations number
5
Categorie Soggetti
General & Internal Medicine
Journal title
SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT
ISSN journal
00367672 → ACNP
Volume
129
Issue
17
Year of publication
1999
Pages
670 - 673
Database
ISI
SICI code
0036-7672(19990501)129:17<670:TISAEP>2.0.ZU;2-I
Abstract
Patients and their physicians are often thrown into doubt by the excretion of apparently intact tablets in stools after oral drug administration. Is t hereto This occurs whenever patients receive certain required. pharmaceutic al forms designed to prolong the rate of drug release. The active compound is continuously released during intestinal passage of these pharmaceutical forms and their insoluble coats are visibly excreted into stools wholly or in part. The assumption that the drug was not released from the tablet in t hese cases is therefore erroneous and no further action is required.