An indium-promoted alternative to the Knoevenagel condensation of aldehydes with methyl acetoacetate

Authors
Paquette, LA Kern, BE Mendez-Andino, J
Citation
La. Paquette et al., An indium-promoted alternative to the Knoevenagel condensation of aldehydes with methyl acetoacetate, TETRAHEDR L, 40(22), 1999, pp. 4129-4132
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
22
Year of publication
1999
Pages
4129 - 4132
Database
ISI
SICI code
0040-4039(19990528)40:22<4129:AIATTK>2.0.ZU;2-X
Abstract
Addition of methyl (E)-4-bromo-3-methoxycrotonate to aldehydes in the prese nce of indium and water delivers P-hydroxy esters, acidic hydrolysis of whi ch leads to Knoevenagel-like adducts. (C) 1999 Elsevier Science Ltd. All ri ghts reserved.