Citation
M. Adiyaman et al., A new method for the preparation of olefins from vicinal diols, TETRAHEDR L, 40(21), 1999, pp. 4019-4022
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039
→ ACNP
Volume
40
Issue
21
Year of publication
1999
Pages
4019 - 4022
Database
ISI
SICI code
0040-4039(19990521)40:21<4019:ANMFTP>2.0.ZU;2-O
Abstract
A novel method is reported for the transformation of vicinal diols to olefi
ns. This methodology consists in the conversion of iodothiocarbonates such
as 16 to olefin 17 with phenyl lithium in excellent yield. Compounds 7 and
12 were prepared by this methodology in order to determine if they would be
recognized by the enzymes, 5-lipoxygenase and 15-lipoxygenase, respectivel
y. (C) 1999 Elsevier Science Ltd. All rights reserved.