At least 6 HLA-DRBI*12 alleles have been identified to date with nucleotide
polymorphism occurring at codons 37, 57-58, 60, 67, 85and 87. In this repo
rt, we describe the identification of another new HLA-DRB1*12 allele: DRB1*
1206. This novel allele was found in an Epstein-Barr vine (EBV)-transformed
Korean B-cell line "K-KT" having the HLA-phenotype A3, 24; B44, 61; Cw3; B
wd, 6; DR12, 13 during full-length cDNA isolation for cell line characteriz
ation and for production of HLA-DR recombinant proteins The allele was iden
tified initially by cycle sequencing of subcloned HLA-DRB full-length cDNA.