H. Martin et al., Clinical laboratory diagnostics and aging. Part 1: Results of the data evaluation of clinical chemical analytes in an aging study, Z GERON GER, 32(2), 1999, pp. 89-96
Citations number
11
Categorie Soggetti
Public Health & Health Care Science","General & Internal Medicine
compared between both groups, are significantly different: Urea, uric acid,
creatinine, triglycerides, total cholesterol, LDL cholesterol, LDL-C/HDL-C
ratio, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl tran
sferase, sodium and ferritin are increased in the older group, whereas HDL
cholesterol, iron, transferrin, and total protein are decreased. The sex di
fferences are more distinct in the group of 44 years old persons than in th
e 63 years old one. These results will be completed by the comparison with
the evaluation of the stored laboratory values of 9923 patients between 20
and 89 years old. The results of the determination of 24 basic blood chemis
try variables from 262 men and 239 women, half of each group 44.4 +/- 0.9 a
nd 63.0 +/- 0.9 (men) and 44.4 +/- 0.9 and 62.8 +/- 0.8 years old (women),
resp., are compared. In men, only 6 analytes show significant differences b
etween the age groups: Alanine aminotransferase down arrow, aspartate amino
transferase down arrow, iron down arrow with p < 0.05; sodium down arrow, c
alcium down arrow, protein (serum) down arrow with p < 0.001. In women, 16
analytes, compared between both groups, are significantly different: Urea,
uric acid, creatinine, triglycerides, total cholesterol, LDL cholesterol, L
DL-C/HDL-C ratio, alanine aminotransferase, alkaline phosphatase, gamma-glu
tamyl transferase, sodium and ferritin are increased in the older group, wh
ereas HDL cholesterol, iron, transferrin, and total protein are decreased.
The sex differences are more distinct in the group of 44 years old persons
than in the 63 years old one. These results will be completed by the compar
ison with the evaluation of the stored laboratory values of 9923 patients b
etween 20 and 89 years old.