Clinical laboratory diagnostics and aging. Part 2: Value of basic blood chemistry analytes as markers of the biological age

In 262 men (about half of them 44.4 +/- 0.9 and 63.0 +/- 0.9 years old, res p.) and 239 women (about half of them 44.4 +/- 0.9 and 62.8 +/- 0.8 years o ld, resp.) the results of 12 clinical chemical analytes were used to calcul ate laboratory indices which were compared with the biological age in accor dance with Ries. The indices were calculated by using concentrations of alk aline phosphatase, iron, total protein, total cholesterol, glucose, uric ac id, urea, HDL cholesterol, creatinine, LDL cholesterol, transferrin, and tr iglycerides. Only in the younger group of women are the correlations betwee n laboratory indices and biological age significant. In the same group, sev eral single parameters also significantly correlate with pre-aging. Among t hem are alkaline phosphatase, the LDL-C/HDL-C ratio, bilirubin, triglycerid es, and glucose.