This study investigated both acute and longer term ("chronic") effects of v
igorous exercise training on affect, nicotine withdrawal, and cigarette cra
ving among women enrolled in a smoking cessation research study. All subjec
ts participated in a 12-week cognitive behavioral smoking cessation program
and were randomly assigned to attend three sessions per week of either a v
igorous exercise program or contact control. Measures of positive and negat
ive affect, cigarette craving, and nicotine withdrawal were administered im
mediately before, and again immediately after the final exercise or contact
session each week of the program. Study I enrolled 24 women who had been a
ssigned to the exercise condition. Significant reductions in negative affec
t, nicotine withdrawal and cigarette craving were observed following exerci
se most weeks of the program. No significant changes in positive affect wer
e observed. In Study II this protocol was repeated among 62 women (44 exerc
ise, 18 contact control) in two consecutive cohorts of the larger study. Si
gnificant reduction were observed in negative affect, nicotine withdrawal a
nd cigarette craving during most weeks of the program among exercise subjec
ts but not contact condition subjects. No chronic (baseline to posttreatmen
t) changes in positive or negative affect, cigarette craving or withdrawal
symptoms were observed in either study. Vigorous exercise appears to produc
e acute improvements in withdrawal symptoms, cigarette craving, and negativ
e affect among sedentary women attempting to quit smoking. (C) 1999 Elsevie
r Science Ltd.