The efficacy and safety of a fixed-combination homeopathic medication (Sinu
sitis PMD(R)) consisting of Lobaria pulmonaria, Luffa operculata, and potas
sium dichromate were investigated in an open-label practice-based study of
119 male and female patients, 12 to 57 years of age, with clinical signs of
acute sinusitis not previously treated. At the first visit, after a mean o
f 4.1 days of treatment, secretolysis had increased significantly and typic
al sinusitis symptoms, such as headache, pressure pain at nerve exit points
, and irritating cough, were reduced. Ninety-nine patients received only th
e test medication. Twenty patients were able to discontinue concomitant med
ication at the first visit. Only one patient needed an antibiotic. The aver
age treatment duration was 2 weeks. At the end of treatment, 81.5% of patie
nts described themselves as symptom free or significantly improved. Adverse
drug effects were not reported.