One hundred sixty patients who underwent a percutaneous intervention for tr
eatment of in-stent restenosis were evaluated on clinical follow-up to dete
rmine the predictors of reintervention, and also to compare rotational athe
rectomy with repeat percutaneous transluminal coronary angioplasty (PTCA) f
or this condition. Current smoking and saphenous vein graft location were t
he independent predictors of target vessel revascularization (TVR), and the
re was no difference in the rate of TVR between rotational atherectomy and
re-PTCA.