We describe a patient with African tick-bite fever who acquired his infecti
on while visiting rural areas of South Africa and then became sick after re
turning to the United States. The dominant clinical feature of his illness
was the presence of multiple, ulcerated lesions (tache noires). Physicians
in the United States and other non-African countries who see travelers retu
rning from southern parts of Africa who give a history of recent tick bite
and/or present with multiple, crusted or vesicular skin lesions should be a
lert to this diagnosis and institute treatment with doxycycline.