Leiomyosarcoma of the esophagus in a patient with Chagasic megaesophagus: Case report and literature review

Leiomyosarcoma constitutes approximately 0.5% of the malignant neoplasias o f the esophagus and its association with megaesophagus has not been describ ed. We report on a case of a woman with dysphagia that was slowly progressi ve from the age of 19 due to chagasic megaesophagus. The woman was subjecte d to cardiomyotomy at the age of 49. She presented a rapid worsening of the dysphagia due to leiomyosarcoma at the age of 61, and was subjected to sub total esophagectomy with cervical esophagogastroplasty. She developed pulmo nary and hepatic metastases 14 months after surgery and died six months lat er.