Interaction between naltrexone, an opioid antagonist, and opioids administered for general anaesthesia

Authors
Tesson, B Bigot-Viale, A Vigue, JP Pierrot, M Granry, JC
Citation
B. Tesson et al., Interaction between naltrexone, an opioid antagonist, and opioids administered for general anaesthesia, ANN FR A R, 18(2), 1999, pp. 230-232
Citations number
7
Categorie Soggetti
Aneshtesia & Intensive Care
Journal title
ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION
ISSN journal
07507658 → ACNP
Volume
18
Issue
2
Year of publication
1999
Pages
230 - 232
Database
ISI
SICI code
0750-7658(199902)18:2<230:IBNAOA>2.0.ZU;2-X
Abstract
We report a case of a probable interaction between sufentanil and naltrexon e, an oral long acting opioid antagonist, prescribed for maintenance of abs tinence in alcoholics and opioid addicts. The interaction resulted in an an tagonisation of the effects of sufentanil and the necessity to increase the dosage. Anaesthetists should be aware of this potential drug interaction. (C) 1999 Elsevier, Paris.