SYNTHETIC STUDIES ON MADUROPEPTIN CHROMOPHORE .1. CONSTRUCTION OF THEARYL ETHER AND ATTEMPTED SYNTHESIS OF THE [7.3.0] BICYCLIC SYSTEM

Authors
NICOLAOU KC KOIDE K
Citation
Kc. Nicolaou et K. Koide, SYNTHETIC STUDIES ON MADUROPEPTIN CHROMOPHORE .1. CONSTRUCTION OF THEARYL ETHER AND ATTEMPTED SYNTHESIS OF THE [7.3.0] BICYCLIC SYSTEM, Tetrahedron letters, 38(21), 1997, pp. 3667-3670
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
21
Year of publication
1997
Pages
3667 - 3670
Database
ISI
SICI code
0040-4039(1997)38:21<3667:SSOMC.>2.0.ZU;2-V
Abstract
The aryl ether system of the maduropeptin chromophore artifact 1 was c onstructed via an aldol type condensation (7 + 6, Schemes 1 and 2, 7 19, Scheme 4), but attempted synthesis and ring closure of aldehyde 2 5 (Scheme 4) to afford the enediyne core of 1 failed. (C) 1987 Elsevie r Science Ltd.