The benefits of a dynamic reaction cell to remove carbon- and chloride-based spectral interferences by ICP-MS

Matrix-derived spectral interferences inhibit the determination of a variet y of elements by ICP-MS. Carbon- and chloride-based matrices render low lev el chromium, manganese, and arsenic determination very difficult, if not im possible, due to the formation of interfering ions. A dynamic reaction cell (DRC) ICP-MS using chemical resolution has been developed to minimize this problem. This work demonstrates that major interferences on m/z 52, 53, 55 , and 75 resulting from (ArC+)-Ar-40-C-13, (ClOH+)-Cl-35-O-16, (ArC+)-Ar-40 -C-13, (ClO+)-Cl-37-O-18, and (ArCl+)-Ar-40-Cl-35, respectively, can be eff ectively reduced, so that ng/L levels of chromium, manganese, and arsenic c an be determined in carbon- and chloride-based matrices.