Microelectronic sensors for measurement of electromagnetic fields of living cells and experimental results

Microelectronic sensors are used for measurements of electromagnetic fields generated by synchronized cultures of yeast cells. Cold sensitive mutant t ub2-401 of Saccharomyces cerevisiae is used. The measured electromagnetic s ignals in the frequency range from 8 to 9 MHz are compared with evolution o f the reassembled microtubules. The detected signals peak in the time inter val 25-30 min and 45-60 min after the release of the cells from the restric tive to the permissive temperature. The first maximum corresponds to the st age when the mitotic spindle is formed and binds chromatids. The second max imum is measured when the processes of anaphase A and of anaphase B take pl ace. (C) 1999 Elsevier Science S.A. All rights reserved.