Bacillus thuringiensis subsp. medellin was grown until sporulation in a 1.1
1 fermenter in batch and intermittent fed-batch culture. At optimum conditi
ons 25 g dry cells l(-1) and 9x10(8) spores ml(-1) were produced. Toxicity
of the final biomass showed a half lethal concentration on third instar Cul
ex quinquefasciatus larvae of 295 ng ml(-1).