Salt and hypertension in end-stage renal disease

Salt and fluid overload play an important role in the pathogenesis of hyper tension in patients with end-stage renal disease. However, in the individua l patient, the relation between salt loading and blood pressure response: i s variable and appears to be influenced by various neurohumoral regulatory mechanisms. This may also have implications for the pathogenesis of structu ral cardiovascular abnormalities in patients with endstage renal disease.