T. Yabuuchi et T. Kusumi, A convenient one-pot synthesis of quaternary alpha-methoxy- and alpha-hydroxycarboxylic acids, CHEM PHARM, 47(5), 1999, pp. 684-686
Several alpha-methoxy- and alpha-hydroxycarboxylic acids have been synthesi
zed by a new one-pot synthesis using ketones, tribromomethane, and potassiu
m hydroxide in methanol and water, respectively, in good yields.