R. Ballini et al., AMBERLYST A-21 AN EXCELLENT HETEROGENEOUS CATALYST FOR THE CONVERSIONOF CARBONYL-COMPOUNDS TO OXIMES, Chemistry Letters, (5), 1997, pp. 475-476
Grimes can be efficiently obtained at room temperature by simply disso
lving the appropriate carbonyl compounds and hydroxylamine hydrochlori
de, in ethanol, with Amberlyst A-21 as catalyst. Good yields of oximes
are obtained, in very short reaction times, even with polifunctionali
zed substrates.