Chaos theories and therapeutic commonalities among depression, Parkinson'sdisease, and cardiac arrhythmias

Citation
Mg. Toro et al., Chaos theories and therapeutic commonalities among depression, Parkinson'sdisease, and cardiac arrhythmias, COMP PSYCHI, 40(3), 1999, pp. 238-244
Citations number
88
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry
Journal title
COMPREHENSIVE PSYCHIATRY
ISSN journal
0010440X → ACNP
Volume
40
Issue
3
Year of publication
1999
Pages
238 - 244
Database
ISI
SICI code
0010-440X(199905/06)40:3<238:CTATCA>2.0.ZU;2-E
Abstract
This report reviews and compares all therapies that have shown efficacy in depression and Parkinson's disease, although some are not in current use an d others are at the experimental stage, They include pharmacological modifi cation of neurotransmitter pathways, electroconvulsive therapy (ECT), sleep deprivation, psychosurgery, electrical stimulation through cerebral electr odes, and transcranial magnetic stimulation. Stemming from a pathophysiolog ical model that stresses the brain as an open, complex, and nonlinear syste m, all therapies have been attributed a common mechanism of action. This re port suggests that the therapeutic isomorphism is related to their ability to help the CNS deactivate cortical-subcortical circuits that are dysfuncti onally coupled. These circuits are self-organized among neurons of their in formational subsystem (rapid conduction) and modulating subsystem (slow con duction), Finally, this report extends the analysis and comparison of these therapies to some cardiac arrhythmias. Copyright (C) 1999 by W.B. Saunders Company.