This paper describes a computational model developed for the diagnosis
of multiple defects. If multiple defects interact, meaning that the c
ues observable for multiple defects are not a sum of the cues observab
le for the component defects, diagnosis is particularly difficult. We
developed a description and classification of the ways cues change whe
n defects interact. A computational model (named Fallot) was implement
ed and a knowledge-base was constructed for the diagnosis of congenita
l heart defects. On each case, Fallot performs recognition-based reaso
ning followed by solution construction and evaluation with the cue com
bination methods. Fallot was tested on cases from hospital files and c
orrectly diagnoses cases with multiple interacting defects for which c
onventional methods are not applicable or fail. (C) 1997 Elsevier Scie
nce B.V.